Project Title: Engineering, evaluation and drive of antimalarial population replacement traits in the mosquito Anopheles gambiae - Transmission zero (I&II)
Project Description: The project titled "Transmission Zero" seeks to develop and test transmission-blocking traits of transgenic malaria mosquitoes with the ultimate aim of eventually eliminating malaria transmission by means of mosquito population replacement. the project is centered on four activities that have been identified as having significant leads times and need to commerce prior to or are a precondition for any significant ramp-up of "Transmission Zero" project activities in Tanzania. it involves the (1) construction of the... The project titled "Transmission Zero" seeks to develop and test transmission-blocking traits of transgenic malaria mosquitoes with the ultimate aim of eventually eliminating malaria transmission by means of mosquito population replacement. the project is centered on four activities that have been identified as having significant leads times and need to commerce prior to or are a precondition for any significant ramp-up of "Transmission Zero" project activities in Tanzania. it involves the (1) construction of the MPL CL3 and its transportation to and installation at the Kingani site in Bagamoyo branch of the IHI, (2) Testing of the MPL CL3 as an infrastructure for conducting laboratory transmission studies using transgenic A gambiae mosquitoes and P. Falciparum parasites, (3) Identification of potential mosquitoes release sites within a single release area, and (4) Stakeholder engagement at the national and local levels. of these activities, ensuring the availability of the MPL CL3 is the most critical as it is a precondition for any type of work with transgenic mosquitoes at IHI Bagamoyo.
Principal Investigator : Fredros Okumu
Department Name : EHES
Time frame: (2019-04-15) - (2026-12-31)
Imperial College of Science, Technology and Medicine (Normal)
Bill and Melinda Gates Foundation (BMGF) (Prime)
External Collaborating Partners
None added yet.